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Study identifier: NCT07313514 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Value of the O-RADS Radiological Classification in Predicting the Malignancy of Ovarian Masses in Children

Condition: Ovarian; Mastopathy  ·  Sponsor: University Hospital, Strasbourg, France

PhaseN/A
Planned participants100
Who can joinAll sexes, 1 Year to 16 Years
Healthy volunteersNo

About this study

When faced with an ovarian mass in a girl, conservative surgery (resection of the mass while preserving healthy ovarian tissue) via laparoscopy remains the most appropriate treatment option. However, this option is no longer indicated for malignant tumors, as this presents a risk of tumor dissemination that can significantly alter the child's subsequent prognosis. Therefore, for any malignant or suspected malignant tumor, radical treatment consisting of oophorectomy or salpingo-oophorectomy, often via laparotomy, is the standard. While keeping this therapeutic principle in mind, differentiating between benign and malignant entities remains the major challenge for clinicians. Furthermore, the diagnostic accuracy of the O-RADS classification based on MRI is not sufficiently established in the literature for children. Our project aims to conduct a multicenter study in the pediatric population to investigate the usefulness of this radiological classification in the preoperative diagnosis of ovarian masses.

This description comes directly from the study's public registry record.

Talk to the study team

Isabelle TALON, MD, PhD  ·  33 3 88 12 72 96  ·  Isabelle.TALON@chru-strasbourg.fr

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Locations (1)

Service de Chirurgie Pédiatrique - CHU de Strasbourg - FranceStrasbourg, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07313514