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Study identifier: NCT07311746 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

Condition: T-cell Prolymphocytic Leukemia · Refractory T-Cell Prolymphocytic Leukemia  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 1/Phase 2
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical research study is to learn if the combination of ruxolitinib with cladribine and venetoclax can help to control the disease in patients with R/R T-PLL.

This description comes directly from the study's public registry record.

Talk to the study team

Tapan Kadia, MD  ·  (713) 563-3534  ·  tkadia@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Texas M. D. Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07311746