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Study identifier: NCT07310719 Synced from ClinicalTrials.gov · July 28, 2026
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A Comparative Study of Intraocular Pressure Control Using Selective Laser Trabeculoplasty and Latanoprost as Initial Treatments for Primary Open Angle Glaucoma and Ocular Hypertension in Lagos State University Teaching Hospital

Condition: Primary Open Angle Glaucoma or Ocular Hypertension  ·  Sponsor: Lagos State Health Service Commission

PhaseNA
Planned participants138
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare the short-term efficacy and safety of selective laser trabeculoplasty (SLT) to 0.005% latanoprost eye drops in lowering intraocular pressure (IOP) as primary therapy in treatment-naïve patients diagnosed as early to moderate primary open-angle glaucoma(POAG) or ocular hypertension (OHT) in the Lagos State University Teaching Hospital, Ikeja. The main questions it aims to answer are: 1. Will Selective Laser Trabeculoplasty be an equally effective treatment option compared with 0.005% Latanoprost eyedrops in reducing Intraocular Pressure when used alone as first-line therapy in Nigerian patients with POAG and OHT? 2. Will Selective Laser Trabeculoplasty record a similar safety profile compared with 0.005% Latanoprost when used independently as a primary therapy? 3. How will the quality of life of patients who undergo Selective Laser Trabeculoplasty treatment compare with patients on 0.005% Latanoprost eyedrops? Participants will be randomized to one of the two intervention groups. Group A(latanoprost group) will use 0.005% latanoprost eye drops every night at 2100hours(9.00pm) west African Time for 3 months. intraocular pressures will be monitored at intervals for a period of 3 months. Group B(SLT group) will have Laser treatment administered as a one-off treatment. intraocular pressures will be monitored at intervals for a period of 3 months. A record of side effects will be documented at each follow up visit

This description comes directly from the study's public registry record.

Talk to the study team

Anne I. Abang-Obi, MBBS  ·  +234 7061339223  ·  iyeundiandeye@gmail.com

Chidinma C. Onyejekwe, FMCOph  ·  +234 7060645714

Always discuss trial participation with your own doctor first.

Locations (1)

Lagos State University teaching Hospital Eye InstituteIkeja, Lagos, NigeriaRecruiting

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Source record: clinicaltrials.gov/study/NCT07310719