● Recruiting

Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy

Condition: Esophageal Carcinoma · Esophageal Adenocarcinoma · Esophagectomy · Sponsor: Sun Yat-sen University

PhaseN/A

Planned participants2500

Who can joinAll sexes, 18 Years to 80 Years

Healthy volunteersNo

About this study

This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Yang, M.D. · 8613560405144 · yanghong@sysucc.org.cn

Yizhang Chen, M.D. candidate · 8613533718832 · chenyizhang@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (6)

Department of Thoracic Surgery, Sun Yat-sen University Cancer Center	Guangzhou, Guangdong, China	Recruiting
Cancer Hospital of Shantou University Medical College	Shantou, Guangdong, China	Recruiting
The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital	Shijiazhuang, Hebei, China	Recruiting
Shanghai Chest Hospital	Shanghai, Shanghai Municipality, China	Recruiting
Sichuan Cancer Hospital	Chengdu, Sichuan, China	Recruiting
0817-2598459	Nanchong, Sichuan, China	Recruiting

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Source record: clinicaltrials.gov/study/NCT07309991