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Study identifier: NCT07306273 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Condition: Pancreatic Adenocarcinoma Locally Advanced  ·  Sponsor: Ruijin Hospital

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study explores the efficacy and safety of irreversible electroporation(IRE) combined with the dual-function antibody PD-1/CTLA-4 (Apalulizumab) for the treatment of locally advanced pancreatic cancer following failure of first-line AG therapy. This research aims to accumulate more clinical evidence and treatment options for second-line therapy in locally advanced pancreatic cancer following failure of first-line regimen.

This description comes directly from the study's public registry record.

Talk to the study team

Zhongmin Wang, Doctor  ·  0086-13901848333  ·  wzm11896@rjh.com.cn

Jingfeng Li, Doctor  ·  0086-13918536451  ·  13918536451@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07306273