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Study identifier: NCT07304284 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trial to Evaluate Immunogenicity Non-Inferiority, Safety and Lot-to-Lot Consistency of Biovac OCV-S to Euvichol®-Plus

Condition: Cholera Vaccination  ·  Sponsor: International Vaccine Institute

PhasePhase 3
Planned participants2824
Who can joinAll sexes, 1 Year to 45 Years
Healthy volunteersYes

About this study

This Phase I/III clinical trial is intended to establish the immunogenicity and safety profile of Biovac OCV-S compared to available WHO pre-qualified vaccine Euvichol®-Plus in healthy adults and children and in adult people living with HIV (PLWH). The lot-to-lot consistency of Biovac OCV-S in healthy adults will also be determined.

This description comes directly from the study's public registry record.

Talk to the study team

Dr. Naveena D'Cor Project Technical Lead / Study Medical Monitor, MD  ·  +82 2 8811 000  ·  naveena.dcor@ivi.int

Beverley Cowper Medical Consultant, MD  ·  BeverleyC@biovac.co.za

Always discuss trial participation with your own doctor first.

Locations (5)

Synergy Biomed Research InstituteDurban, Eastern Cape, South AfricaNot Yet Recruiting
Perinatal HIV Research Unit (PHRU)Johannesburg, Gauteng, South AfricaRecruiting
Wits Vaccines & Infectious Diseases Analytics (VIDA) Research UnitJohannesburg, Gauteng, South AfricaNot Yet Recruiting
SAMRC Chatworth CRSDurban, KwaZulu-Natal, South AfricaRecruiting
SAMRC Isipingo CRSDurban, KwaZulu-Natal, South AfricaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07304284