Condition: Acute Myeloid Leukemia · Sponsor: University of California, Davis
This phase II trial studies how well giving olutasidenib with azacitidine, followed by olutasidenib maintenance, works in treating patients with IDH1-mutated acute myeloid leukemia (AML) who have received prior treatment with venetoclax plus a hypomethylating agent (HMA-Ven). Olutasidenib and azacitidine may inhibit the growth of cancer cells by blocking certain enzymes required for cell growth. Maintenance therapy can help prevent or delay cancer from coming back. Olutasidenib with azacitidine followed by olutasidenib maintenance may be effective in treating patients with IDH1-mutated AML who have received prior HMA-Ven.
This description comes directly from the study's public registry record.
Office of Clinical Research · 916-382-6970 · OCRReferral@health.ucdavis.edu
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| University of California Davis Comprehensive Cancer Center | Sacramento, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07304011