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Study identifier: NCT07303738 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1)

Condition: Feeding Difficulties · Aspiration · Gastrostomy  ·  Sponsor: Boston Children's Hospital

PhasePhase 4
Planned participants60
Who can joinAll sexes, 5 Years to 21 Years
Healthy volunteersNo

About this study

We will perform an acute physiology study comparing three different diets-an amino acid-based formula, a low bile acid-binding blenderized diet, or a high bile acid-binding blenderized diet administered through gastrostomy tube. We will determine the differences in gastric and salivary bile acid concentrations between participants over the 4 hour post-prandial timeframe. Participants who regularly receive an amino acid-based formula will receive an amino acid-based formula during the study and participants who regularly receive a blenderized feed will receive a blenderized feed during the study. Only participants who regularly receive blenderized feeds will be randomized to receive either the high or low bile acid binding blenderized feed.

This description comes directly from the study's public registry record.

Talk to the study team

Rachel Rosen  ·  617-355-0897  ·  rachel.rosen@childrens.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07303738