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Study identifier: NCT07302802 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice

Condition: Monogenic Obesity  ·  Sponsor: Prof. Dr. Martin Wabitsch

PhaseN/A
Planned participants70
Who can joinAll sexes, 12 Years to 21 Years
Healthy volunteersNo

About this study

This observational study aims to assess the effect of once-weekly s.c. semaglutide 2.4 mg as an adjunct to a calorie-reduced diet and increased physical activity on weight loss, change in hunger, body composition, depression, and quality of life after 68 weeks of treatment in adolescents diagnosed with monogenic obesity in routine clinical care.

This description comes directly from the study's public registry record.

Talk to the study team

Martin Wabitsch, Prof. Dr.  ·  +4973150057401  ·  martin.wabitsch@uniklinik-ulm.de

Stefanie Zorn, Dr.  ·  +4973150057457  ·  stefanie.zorn@uniklinik-ulm.de

Always discuss trial participation with your own doctor first.

Locations (7)

Assistance Publique-Hôpitaux de Paris (AP-HP), Trousseau Hospital Paris, Pediatric Nutrition DepartmentParis, FranceNot Yet Recruiting
Institute for Experimental Pediatric Endocrinology, Charité Universitätsmedizin BerlinBerlin, GermanyNot Yet Recruiting
University Hospital for Children and Adolescents, Center for Pediatric Research, Medical Faculty, University of LeipzigLeipzig, GermanyNot Yet Recruiting
Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine, Ulm University Medical CentreUlm, GermanyRecruiting
University Medical Center Rotterdam, Erasmus MC-Sophia Children's HospitalRotterdam, NetherlandsNot Yet Recruiting
Departments of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de MadridMadrid, SpainNot Yet Recruiting
Wellcome-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research CentreCambridge, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07302802