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Study identifier: NCT07301255 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults

Condition: Asthma  ·  Sponsor: Enveda Therapeutics

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and potential efficacy of ENV-294 in adults with moderate to severe asthma who are receiving background treatment with inhaled corticosteroids (ICS) and long-acting beta₂-agonists (LABA). Participants will take oral ENV-294 or placebo once daily for 12 weeks. The study includes a screening period of up to 28 days before randomization to confirm eligibility. Study visits and assessments will be conducted to monitor safety, measure drug levels in the blood, and evaluate effects on asthma control and lung function.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Operations  ·  env-294.clinicaltrials@enveda.com

Always discuss trial participation with your own doctor first.

Locations (14)

Enveda Investigative SiteBirmingham, Alabama, United StatesRecruiting
Enveda Investigative SiteLos Angeles, California, United StatesRecruiting
Enveda Investigative SiteSan Jose, California, United StatesRecruiting
Enveda Investigative SiteColorado Springs, Colorado, United StatesRecruiting
Enveda Investigative SiteHialeah, Florida, United StatesRecruiting
Enveda Investigative SiteAlbany, Georgia, United StatesRecruiting
Enveda Investigative SiteOwensboro, Kentucky, United StatesRecruiting
Enveda Investigative SiteSouthfield, Michigan, United StatesRecruiting
Enveda Investigative SiteSt Louis, Missouri, United StatesRecruiting
Enveda Investigative SiteClackamas, Oregon, United StatesRecruiting
Enveda Investigative SiteMedford, Oregon, United StatesRecruiting
Enveda Investigative SiteNorth Charleston, South Carolina, United StatesRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07301255