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Study identifier: NCT07301034 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Condition: Myocardial Infarction  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants332
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is testing the effect of ziltivekimab on reducing plaque in the blood vessels of the heart, specifically aiming to manage or reduce atherosclerotic plaque. The purpose of the study is to determine whether ziltivekimab can effectively reduce this plaque. Participants will either receive ziltivekimab (the active medicine) or a placebo (a dummy medicine with no effect on the body), with the treatment assignment decided by chance. It is important to note that ziltivekimab is not yet approved in any country or region worldwide; therefore, it is a new medicine that doctors cannot prescribe. The study will last for about 15 months.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (20)

Medizinische Universität WienVienna, AustriaNot Yet Recruiting
Aalborg Universitetshospital Hjertemedicinsk AfdelingGistrup, DenmarkNot Yet Recruiting
Rigshospitalet - Kardiologisk ForskningsenhedKøbenhavn Ø, DenmarkNot Yet Recruiting
Azienda Ospedaliera San Giovanni AddolorataRome, Lazio, ItalyNot Yet Recruiting
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIIIBergamo, Lombardy, ItalyNot Yet Recruiting
DAI Scienze Mediche - UOC EndocrinologiaMessina, Sicily, ItalyNot Yet Recruiting
Presidio Ospedaliero di RivoliRivoli, To, ItalyNot Yet Recruiting
Ospedale Policlinico San MartinoGenova, ItalyNot Yet Recruiting
AOU Maggiore della Carità di Novara - Dipartimento Toraco-Cardio-Vascolare - SCDU CardiologiaNovara, ItalyNot Yet Recruiting
Azienda Ospedaliera Universitaria San Luigi Gonzaga - S.C.D.O. Microcitemie e malattie rare ematologicheOrbassano, ItalyNot Yet Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCSRome, ItalyNot Yet Recruiting
IRCCS Policlinico San DonatoSan Donato Milanese, ItalyNot Yet Recruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07301034