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Study identifier: NCT07300943 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study in Advanced Solid Tumor Patients

Condition: Advanced Solid Tumor  ·  Sponsor: Callio Therapeutics

PhasePhase 1/Phase 2
Planned participants306
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study will be conducted in 2 phases: Phase 1: Dose-escalation and Dose Level Expansion, Phase 1 will determine the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE). Phase 2: Tumor-Specific Expansions with Dose Optimization, Phase 2 will further evaluate CLIO-8221 in tumor-specific expansion cohorts to optimize dosing and assess preliminary efficacy.

This description comes directly from the study's public registry record.

Talk to the study team

CMO  ·  206-602-3134  ·  clinical@calliotx.com

Always discuss trial participation with your own doctor first.

Locations (11)

DFCIBoston, Massachusetts, United StatesNot Yet Recruiting
Sarah Cannon Research Institute 335 24th Avenue North, Suite 400Nashville, Tennessee, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
START San AntonioSan Antonio, Texas, United StatesRecruiting
START MountainWest Valley City, Utah, United StatesRecruiting
Scientia Clinical ResearchRandwick, New South Wales, AustraliaRecruiting
Integrated Clinical Oncology Network Pty LtdSouth Brisbane, Queensland, AustraliaRecruiting
Peter Maccallum Cancer CentreBox Hill, Victoria, AustraliaRecruiting
AlfredHealthHeidelberg, Victoria, AustraliaRecruiting
Royal Melbourne HospitalMelbourne, Victoria, AustraliaRecruiting
Linear Clinical Research LtdNedlands, Western Australia, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT07300943