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Study identifier: NCT07300241 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

Condition: Clear Cell Renal Cell Carcinoma · Renal Cell Carcinoma · RCC  ·  Sponsor: Neomorph, Inc

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The NEO-811-101 study is an open-label, first-in-human, Phase 1/2 dose escalation and expansion study testing NEO-811, an ARNT molecular glue degrader, in subjects with locally advanced or metastatic non-resectable clear cell renal cell carcinoma. The study will test NEO-811 initially as a monotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Sara Weymer  ·  +1 858-428-9800  ·  clinicaltrials@neomorph.com

Always discuss trial participation with your own doctor first.

Locations (11)

NEO-811 Los Angeles SiteDuarte, California, United StatesRecruiting
NEO-811 San Diego SiteSan Diego, California, United StatesRecruiting
NEO-811 Connecticut SiteNew Haven, Connecticut, United StatesRecruiting
NEO-811 Chicago SiteZion, Illinois, United StatesRecruiting
NEO-811 Grand Rapids SiteGrand Rapids, Michigan, United StatesRecruiting
NEO-811 Long Island SiteLake Success, New York, United StatesRecruiting
NEO-811 NYC SiteNew York, New York, United StatesRecruiting
NEO-811 South Carolina SiteMyrtle Beach, South Carolina, United StatesRecruiting
NEO-811 Dallas SiteDallas, Texas, United StatesRecruiting
NEO-811 Houston SiteHouston, Texas, United StatesRecruiting
NEO-811 Virginia SiteFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07300241