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Study identifier: NCT07300150 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

Condition: Colorectal Cancer · Pancreatic Cancer · Non-Small Cell Lung Cancer  ·  Sponsor: PAQ Therapeutics, Inc.

PhasePhase 1
Planned participants210
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of this study is to evaluate the safety and tolerability, determine the maximally tolerated dose (MTD) and/or recommended Phase 2 dose(s) (RP2D) of PT0511 in adult participants with solid tumors as monotherapy and in combination with cetuximab in participants with colorectal cancer (CRC).

This description comes directly from the study's public registry record.

Talk to the study team

PAQ Therapeutics  ·  781-819-2949  ·  ClinicalTrials@paqtx.com

Always discuss trial participation with your own doctor first.

Locations (9)

Dana-Farber/Massachusetts General Hospital, IncBoston, Massachusetts, United StatesRecruiting
New Experimental Therapeutics of San Antonio LLCSan Antonio, Texas, United StatesRecruiting
START - South Texas Accelerated Research Therapeutics, LLCSan Antonio, Texas, United StatesRecruiting
START Mountain RegionWest Valley City, Utah, United StatesRecruiting
NEXT VirginiaFairfax, Virginia, United StatesRecruiting
Samsung Medical CenterSeoul, South KoreaRecruiting
Seoul National University Bundang HospitalSeoul, South KoreaRecruiting
Seoul National University HospitalSeoul, South KoreaRecruiting
Severance Hospital, Yonsei University Health SystemSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07300150