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Study identifier: NCT07299357 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prospective Observational Trial of Image-guided Ablative STereotactic bOdy Radiation Therapy for Primary kidNey Cancer: the STONE Trial

Condition: Renal Cancer  ·  Sponsor: Istituto Clinico Humanitas

PhaseN/A
Planned participants53
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study objective is to evaluate the use of Stereotactic Body Radiotherapy (high dose of radiation in a few fractions) to cure primary renal cancer in those patients that are not indicated to surgery (high risk of complications, refusal of the patient). This therapy is already used in clinical setting for many tumors with good tolerance as it is not invasive, does not require anesthesia and hospitalization making it suitable for elderly people and frail patients. However there are not enough information regarding the use of ablative doses for the cure of renal cancer and for this reason this study aims to support the use of Stereotactic Body Radiotherapy as a standard of care for inoperable primary renal tumor. This is an observational study, so it collects data from clinical pratice only and does not request study specific procedures.

This description comes directly from the study's public registry record.

Talk to the study team

Ciro Franzese, MD, radiation oncologist  ·  +39 0282247454  ·  ciro.franzese@hunimed.eu

Laura Bonavita, Master's degree  ·  +390282247026  ·  laura.bonavita@humanitas.it

Always discuss trial participation with your own doctor first.

Locations (2)

Humanitas PIO XMilan, Milan, ItalyNot Yet Recruiting
Irccs Humanitas Research HospitalRozzano, Milan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07299357