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Study identifier: NCT07298473 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

Condition: Atrial Fibrillation (AF) · Persistent Atrial Fibrillation · Paroxysmal Atrial Fibrillation (PAF)  ·  Sponsor: Medtronic Cardiac Ablation Solutions

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Conquer-AF is a prospective, multi-center, interventional, non-randomized clinical study that will enroll up to 400 subjects at up to 30 sites across the United States, Europe, and Australia. Subjects diagnosed with symptomatic recurrent paroxysmal or persistent atrial fibrillation after a single prior ablation procedure will be enrolled in this study. Each subject will undergo a study index redo ablation procedure using the Sphere-9 Catheter and Affera Ablation System and will be followed for 12 months. The expected total study duration (from time of first enrollment to the exit of last enrolled subject) is approximately 2 years.

This description comes directly from the study's public registry record.

Talk to the study team

Ryan S Radtke, Bachelors of Science- Biology  ·  712-941-9372  ·  ryan.s.radtke@medtronic.com

Always discuss trial participation with your own doctor first.

Locations (30)

University of Alabama at Birmingham (UAB) HospitalBirmingham, Alabama, United StatesNot Yet Recruiting
Scripps Green HospitalLa Jolla, California, United StatesNot Yet Recruiting
Cedars Sinai Medical CenterLos Angeles, California, United StatesNot Yet Recruiting
NCH Rooney Heart InstituteNaples, Florida, United StatesRecruiting
AdventHealth Cardiovascular Research InstituteOrlando, Florida, United StatesNot Yet Recruiting
Piedmont Heart InstituteAtlanta, Georgia, United StatesNot Yet Recruiting
Memorial Health University Medical CenterSavannah, Georgia, United StatesNot Yet Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Kansas City Heart Rhythm Institute (Midwest Heart and Vascular Specialist)Kansas City, Missouri, United StatesNot Yet Recruiting
Northwell Health Lenox Hill HospitalNew Hyde Park, New York, United StatesNot Yet Recruiting
NYU Langone Medical CenterNew York, New York, United StatesNot Yet Recruiting
Montefiore Medical CenterThe Bronx, New York, United StatesNot Yet Recruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07298473