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Study identifier: NCT07298447 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Donidalorsen Treatment in Children With Hereditary Angioedema

Condition: Hereditary Angioedema (HAE)  ·  Sponsor: Ionis Pharmaceuticals, Inc.

PhasePhase 3
Planned participants20
Who can joinAll sexes, 2 Years to 11 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of donidalorsen in pediatric participants with hereditary angioedema (HAE) Type I (HAE-1) or Type II (HAE-2).

This description comes directly from the study's public registry record.

Talk to the study team

Ionis Pharmaceuticals, Inc.  ·  (844) 201-3192  ·  IonisDonidalorsenPediatric@clinicaltrialmedia.com

Always discuss trial participation with your own doctor first.

Locations (10)

Ionis Investigative SiteSanta Monica, California, United StatesRecruiting
Ionis Investigative SiteMiami, Florida, United StatesRecruiting
Ionis Investigative SiteSt Louis, Missouri, United StatesRecruiting
Ionis Investigative SiteCincinnati, Ohio, United StatesRecruiting
Ionis Investigative SiteHershey, Pennsylvania, United StatesRecruiting
Ionis Investigative SiteMilan, ItalyRecruiting
Ionis Investigative SitePadova, ItalyRecruiting
Ionis Investigative SiteSan Donato Milanese, ItalyRecruiting
Ionis Investigative SiteWarsaw, PolandRecruiting
Ionis Investigative SiteBarcelona, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07298447