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Study identifier: NCT07298421 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess the Pharmacokinetics, Effectiveness and Safety of Afimkibart for Induction and Maintenance Therapy in Children With Moderately to Severely Active Crohn's Disease

Condition: Moderately to Severely Active Crohns Disease  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants100
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

This phase III, double-blind, multi-center treat-through study will evaluate the efficacy and safety of Afimkibart (also known as RO7790121) in children with moderately to severely active Crohn's Disease (CD).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: CP45906 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (7)

Royal Children's HospitalParkville, Victoria, AustraliaRecruiting
Perth Children's HospitalNedlands, Western Australia, AustraliaRecruiting
National Taiwan University HospitalTaipei, TaiwanRecruiting
Chulalongkorn UniversityBangkok, ThailandRecruiting
Siriraj HospitalBangkok, ThailandRecruiting
Ramathibodi HospitalBangkok, ThailandRecruiting
Sheffield Childrens HospitalSheffield, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07298421