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Study identifier: NCT07298057 Synced from ClinicalTrials.gov · July 29, 2026
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Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics

Condition: Periodontitis, Diabetes Mellitus Type 2  ·  Sponsor: Case Western Reserve University

PhaseEARLY_Phase 1
Planned participants42
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Periodontitis is a prevalent chronic inflammatory disease that exacerbates systemic inflammation and poses challenges for glycemic control in diabetic patients. While scaling and root planing (SRP) remains the cornerstone of periodontal therapy, adjunctive treatments such as Arestin (minocycline microspheres) have shown promise in enhancing clinical outcomes. This study aims to evaluate the impact of adding Arestin to SRP on periodontal pocket closure, glycemic control, and systemic inflammation in diabetic patients with periodontitis.

This description comes directly from the study's public registry record.

Talk to the study team

Gian Pietro Schincaglia, DDS, PhD  ·  216-368-4412  ·  gxs486@case.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Case Western Reserve UniversityCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07298057