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Study identifier: NCT07297849 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Eyelid Closure in Keratometry

Condition: Dry Eye · Ocular Surface Disease  ·  Sponsor: Vienna Institute for Research in Ocular Surgery

PhaseNA
Planned participants29
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cataract surgery is one of the most common performed surgeries in the world. While in the early beginnings of cataract surgery, visual rehabilitation was the main goal of the procedure, refractive outcome and subsequent relative spectacles independency is gaining increasing importance in patients' demands. Due to the improvements in measurement techniques and prediction formulas, the prediction of postoperative refraction is possible with high accuracy. However, there are still some sources of error that lead to deviations of predicted postoperative refraction. For instance, it was shown that tear film osmolarity, an established biomarker for dry eye disease (DED), plays an important role in preoperative precision of keratometry measurements. Keratometry, the measurement of corneal curvature, is an important part of preoperative biometry. Errors in preoperative keratometry measurements lead to nearly one-to-one deviations from the predicted refraction. Therefore, proper keratometry measurements are a key element in intraocular lens (IOL) power calculations. To counteract the issue of DED in preoperative biometry, the principle of using lubricating eye drops before ocular biometry has been investigated and it was shown that the use of ocular lubricants may lead to increased variability of keratometry measurements. From our clinical observations, another possible mechanism to improve keratometry is eyelid closure for some minutes. In contrast to the long-term use of ocular lubr…

This description comes directly from the study's public registry record.

Talk to the study team

Andreas Schlatter, MD  ·  +43 1 91021 57564  ·  office@viros.at

Always discuss trial participation with your own doctor first.

Locations (1)

Vienna Institute for Research in Ocular Surgery (VIROS), Department of OphthalmologyVienna, State of Vienna, AustriaRecruiting

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Source record: clinicaltrials.gov/study/NCT07297849