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Study identifier: NCT07295847 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of AZD0120 in Autoimmune Diseases

Condition: Systemic Sclerosis · Idiopathic Inflammatory Myopathies · Rheumatoid Arthritis  ·  Sponsor: AstraZeneca

PhasePhase 1
Planned participants27
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This trial is a Phase 1b, open-label, multi-center, clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and tolerability in adult participants with systemic sclerosis (SSc), idiopathic inflammatory myopathies (IIM), or difficult-to-treat rheumatoid arthritis (D2T RA).

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (22)

Research SiteTucson, Arizona, United StatesNot Yet Recruiting
Research SiteStanford, California, United StatesNot Yet Recruiting
Research SiteChicago, Illinois, United StatesNot Yet Recruiting
Research SiteAnn Arbor, Michigan, United StatesRecruiting
Research SiteSt Louis, Missouri, United StatesNot Yet Recruiting
Research SiteNew York, New York, United StatesRecruiting
Research SiteChapel Hill, North Carolina, United StatesNot Yet Recruiting
Research SiteSeattle, Washington, United StatesNot Yet Recruiting
Research SiteDarlinghurst, AustraliaRecruiting
Research SiteWaratah, AustraliaNot Yet Recruiting
Research SiteBerlin, GermanyNot Yet Recruiting
Research SiteErlangen, GermanyNot Yet Recruiting

+ 10 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07295847