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Study identifier: NCT07295483 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Predictors of Long-Term Evolution in Long COVID; 4-Year Follow-Up. (BioICOPER Follow-up Study)

Condition: Persistent COVID Condition  ·  Sponsor: Instituto de Investigación Biomédica de Salamanca

PhaseN/A
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Long COVID (persistent COVID) represents a major global health challenge due to its high prevalence (approximately 7%), significant impact on quality of life, and socioeconomic burden. Despite extensive research, diagnostic tools to objectively identify or predict long COVID evolution are still lacking. The BioICOPER Follow-up Study aims to analyze the influence of biomarker evolution on clinical symptomatology (particularly chronic fatigue) and vascular health after four years of follow-up among 400 participants previously included in the original BioICOPER cohort. Advanced proteomic analysis, vascular function assessment, and machine-learning-based predictive modeling will be used to identify biomarkers associated with disease progression, stratified by sex. This project will contribute to personalized clinical management of long COVID and improved diagnostic and therapeutic strategies in primary care.

This description comes directly from the study's public registry record.

Talk to the study team

Manuel Angel Gómez Marcos, MD, PhD  ·  +346751143551  ·  magomez@usal.es

Always discuss trial participation with your own doctor first.

Locations (1)

Av. de Portugal 83. Planta 2Salamanca, Salamanca, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07295483