Condition: Hepatocellular Carcinoma (HCC) · Sponsor: Tuen Mun Hospital
The goal of this clinical trial is to compare the safety and efficacy of sequential Transarterial Chemoembolization (TACE) and Stereotactic body radiation therapy (SBRT) versus Y90-radioembolisation (SIRT), followed by systemic therapy in patients with large, locally advanced, unresectable Hepatocellular carcinoma (HCC). The main question it aims to answer is whether Sequential TACE-SBRT potentially gives longer Progression-free survival (PFS) benefit with similar toxicities as compared with Y90 SIRT. Participants will be recruited via multidisciplinary meetings (MDTs) with hepatobiliary surgeons, medical hepatologists and radiologists with consistent, strict considerations on eligibility and treatment alternatives. Eligible patients will be randomized in 1:1 ratio to received one of the two treatment arms.
This description comes directly from the study's public registry record.
Sean Man Natalie WONG · 852-24685088 · wsm011@ha.org.hk
Man TONG · 852-24685086 · tm326@ha.org.hk
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| Tuen Mun Hospital | Hong Kong, Hong Kong | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07293468