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Study identifier: NCT07293260 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

Condition: Cardiovascular Disease  ·  Sponsor: Amgen

PhasePhase 3
Planned participants406
Who can joinAll sexes, 35 Years to 80 Years
Healthy volunteersNo

About this study

The primary objective of this trial is to evaluate the effect of olpasiran, compared to placebo, on non-calcified plaque (NCP) volume as measured by Coronary Computed Tomography Angiography (CCTA).

This description comes directly from the study's public registry record.

Talk to the study team

Amgen Call Center  ·  866-572-6436  ·  medinfo@amgen.com

Always discuss trial participation with your own doctor first.

Locations (40)

Bridgeport HospitalBridgeport, Connecticut, United StatesRecruiting
Jacksonville Center for Clinical ResearchJacksonville, Florida, United StatesRecruiting
Midwest Heart and Vascular SpecialistsOverland Park, Kansas, United StatesRecruiting
Flourish BowieBowie, Maryland, United StatesRecruiting
Montefiore Medical Center - BronxPhiladelphia, Pennsylvania, United StatesRecruiting
Vital Heart and VeinHumble, Texas, United StatesRecruiting
Advara HeartCare WesleyAuchenflower, Queensland, AustraliaRecruiting
University of The Sunshine Coast Clinical Trials, Sippy DownsSippy Downs, Queensland, AustraliaRecruiting
Advara HeartCare LeabrookLeabrook, South Australia, AustraliaRecruiting
North York Diagnostic and Cardiac CentreVaughan, Ontario, CanadaRecruiting
Peking University First HospitalBeijing, Beijing Municipality, ChinaRecruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, ChinaRecruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07293260