Condition: Tobacco Use Disorder · Addiction Nicotine · Sponsor: Waypoint Centre for Mental Health Care
The goal of this clinical trial is to examine whether a 5-day course of bilateral accelerated deep transcranial magnetic stimulation (aTMS) is a feasible treatment to help adults (18-65) with Tobacco Use Disorder to quit smoking. This study aims to enroll 30-40 participants and will examine treatment tolerability, treatment acceptability, participant retention, and adherence to scheduled treatment sessions. There are two key objectives and hypotheses: Objective 1: To evaluate whether a 1-week course of bilateral aTMS (4 sessions per day for 5 days) is feasible and tolerable as a smoking cessation treatment. Hypothesis 1: Feasibility will be demonstrated by acceptable tolerability, acceptability, retention, and adherence, with a practical target of 30 out of 40 participants completing the treatment. Objective 2: To explore how aTMS affects smoking outcomes, including: * Point-prevalence abstinence at end of treatment and at Weeks 3, 5, and 9. * Prolonged/continuous abstinence at Weeks 13 and 26. * Craving, cigarettes per day, and dependence severity. Hypothesis 2: Participants will show improvements on these outcomes from post-treatment through follow-up.
This description comes directly from the study's public registry record.
Florence Tang, MA · 705-549-3181 · ftang@waypointcentre.ca
Vincent Wang, MD · 647-522-3415 · xi-yu.wang@camh.ca
Always discuss trial participation with your own doctor first.
| Waypoint Centre for Mental Health Care | Penetanguishene, Ontario, Canada | Recruiting |
| Sunnybrook Health Sciences Centre | Toronto, Ontario, Canada | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07292883