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Study identifier: NCT07292870 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Biologicals in Management of Intra-Bony Defects

Condition: Intra-bony Pockets · Periodontitis  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The aim is of this study is to evaluate and compare the effects (clinical and radiological) of different biomaterials on the repair of bone defects around the teeth. When participating in this study, persons will be scheduled for local surgical intervention of the gums. Under local anaesthesia, the gums will be opened minimally to gain insight into the underlying bone defect. After the bone defect has been made completely free of inflammation, they will be randomly assigned to one of the groups below and the biomaterials for this group will be used to fill the defect around your teeth. The different biomaterials are artificial bone + amelogenin; artificial bone + hyaluronic acid; artificial bone + blood preparation (L-PRF) or blood preparation alone. Then the gums will be closed again with a suture and they will receive the necessary instructions regarding the procedure.

This description comes directly from the study's public registry record.

Talk to the study team

Ana B Castro Sarda, Professor  ·  +32 16 332816  ·  ana.castro@uzleuven.be

Lieve Desmet, secretary  ·  +32 16 332407  ·  lieve.desmet@kuleuven.be

Always discuss trial participation with your own doctor first.

Locations (1)

UZLeuven, Campus St. Raphaël, Department Oral Health Sciences, PeriodontologyLeuven, Vlaams Brabant, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT07292870