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Study identifier: NCT07290634 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion

Condition: Thromboembolus · Massive Blood Transfusion; Thrombocytopenia · Trauma  ·  Sponsor: Zeliha Alicikus

PhaseN/A
Planned participants4
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to compare the incidence of thromboembolic complications among trauma patients receiving PCC, rFVIIa, both agents, or neither during massive transfusion. Secondary objectives include comparing mortality, transfusion requirements, intensive care unit (ICU) and hospital length of stay, ventilator-free days, and the incidence of transfusion-associated adverse events such as transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO). Subgroup analyses will evaluate outcomes in patients with and without laboratory-confirmed TIC (INR \>1.2).

This description comes directly from the study's public registry record.

Talk to the study team

Ayten SARAÇOĞLU, Prof,MD  ·  +1 (904) 524-4331  ·  anesthesiayten@gmail.com

Tolga SARAÇOĞLU, Prof,MD  ·  +1 (904) 524-5932  ·  kemaltolgasaracoglu@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

UF Health Jacksonville (Shands Hospital)Jacksonville, Florida, United StatesRecruiting
UF Health Jacksonville (Shands Hospital)Jacksonville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07290634