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Study identifier: NCT07290582 Synced from ClinicalTrials.gov · July 29, 2026
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Phrenic Infiltration as Cryoanalgesia Adjuvant for Early Postoperative Pain Following the Nuss Procedure

Condition: Pectus Excavatum · Cryo Analgesia · Phrenic Nerve-related Diaphragmatic Impairment  ·  Sponsor: Papa Giovanni XXIII Hospital

PhaseN/A
Planned participants50
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational ambispective study is to compare the effectiveness of two pain management strategies in pediatric patients undergoing the Nuss procedure for pectus excavatum. The main questions it aims to answer are: Does the addition of phrenic Infiltration as Cryo Adjuvant (PhICA) to earlier percutaneous intercostal cryoanalgesia (EPIC) reduce postoperative pain scores compared to EPIC alone? Does the combined EPIC + PhICA technique reduce the need for rescue tramadol compared to EPIC alone? Do the two approaches differ in: length of hospital stay, time to transition to oral therapy, and time to mobilization? Are there any side effects Researchers will compare patients who received EPIC alone to patients who received EPIC + PhICA to see if the combined technique provides superior pain control. Participants: Received either EPIC alone or EPIC combined with PhICA as part of their surgical anesthesia plan Had pain levels assessed using the Numeric Rating Scale (NRS) at regular postoperative intervals Were monitored for rescue tramadol requirements, medicaments taken, length of hospital stay, and mobilization timing Were monitored for any technique-related complication

This description comes directly from the study's public registry record.

Talk to the study team

Stefano Mariconti, MD  ·  +39 035.267.5150 - 5149  ·  smariconti@asst-pg23.it

Always discuss trial participation with your own doctor first.

Locations (1)

Sc Ricerca Clinica, Sviluppo E InnovazioneBergamo, BG, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07290582