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Study identifier: NCT07290244 Synced from ClinicalTrials.gov · July 29, 2026
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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Condition: Open Angle Glaucoma (OAG) · NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)  ·  Sponsor: Life Biosciences Inc.

PhasePhase 1
Planned participants18
Who can joinAll sexes, 40 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the safety and tolerability of a single dose of ER-100 in adults with optic nerve conditions, specifically Open Angle Glaucoma (OAG) and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). The main questions it aims to answer are: * Is ER-100 safe when given as a single dose to people with OAG or NAION * What side effects may occur, if any, after taking ER-100? Participants will: * Receive a single dose of ER-100 * Undergo safety assessments including detailed eye examination and laboratory tests * Provide body fluid samples (tears, saliva, feces, urine) to help researchers understand how the drug is processed and cleared from the body * Complete questionnaires about their quality of life * Be followed for up to 5 years to monitor long-term health and vision outcomes

This description comes directly from the study's public registry record.

Talk to the study team

Life Biosciences  ·  (857) 400-9245  ·  ER100trial@lifebiosciences.com

Always discuss trial participation with your own doctor first.

Locations (4)

Global Research Management, Inc.Glendale, California, United StatesRecruiting
Mass Eye and EarBoston, Massachusetts, United StatesRecruiting
Columbia University Irving Medical Center/Edward S. Harkness Eye InstituteNew York, New York, United StatesRecruiting
Charleston Neuroscience InstituteCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07290244