Condition: Subjective Cognitive Decline (SCD) · Mild Cognitive Impairment (MCI) · Alzheimer Dementia (AD) · Sponsor: Aristotle University Of Thessaloniki
This randomized study tests whether a new multicomponent Positive Psychology program can improve cognition and wellbeing in older adults at the earliest stages of dementia-related decline. About 128 participants with Subjective Cognitive Decline or Mild Cognitive Impairment will be enrolled. Half will be randomized to the Positive Psychology program and half to Treatment As Usual (TAU). The program consists of weekly, small-group online sessions for \~24 weeks plus brief home practices. All participants (both arms) will complete questionnaires and cognitive tests at baseline, during treatment, post-treatment, and 9-month follow-up. Primary question: Do participants receiving the Positive Psychology program show better cognitive and brain-function outcomes than TAU at post-treatment and at 9 months? Secondary question: Are effects larger for SCD than MCI? No medicines are used and risks are minimal. If effective, this scalable, low-cost, non-pharmacological approach could complement usual care for people in very early cognitive decline.
This description comes directly from the study's public registry record.
Dimitra Vasileiou, M.Sc., PhD candidate · +30 6987304327 · dvasilea@psy.auth.gr
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| Aristotle University of Thessaloniki | Thessaloniki, Greece | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07289061