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Study identifier: NCT07288437 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Deep Brain Stimulation for Spinocerebellar Ataxia

Condition: Spinocerebellar Ataxia (SCA) · Spinocerebellar Ataxia Type 6  ·  Sponsor: University of California, San Francisco

PhaseNA
Planned participants5
Who can joinAll sexes, 21 Years to 89 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to test the safety of placing Deep Brain Stimulators (DBS) in the cerebellum and using electrical stimulation of that part of the brain to treat symptoms related to the participants spinocerebellar ataxia. Five adults diagnosed with spinocerebellar ataxia type 6 (SCA6) with inadequate cerebellar symptom relief will be implanted with a Medtronic Percept Primary Cell Neurostimulator. The device will be implanted into the dentate nucleus, which is a structure located within the cerebellum that is responsible for controlling movement and balance. Specifically, the investigators will be using adaptive deep brain stimulation (aDBS), which analyzes brain signals and automatically adjusts the strength, timing, and pattern of stimulation according to the patient's needs at any given moment. This study will evaluate the feasibility, safety, and tolerability of aDBS in SCA6 patients.

This description comes directly from the study's public registry record.

Talk to the study team

Marta San Luciano Palenzuela, MD, PhD  ·  (415) 353-2311  ·  Marta.SanLucianoPalenzuela@ucsf.edu

Karson J Franjieh, BS  ·  415-755-8954  ·  karson.franjieh@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (2)

UCSF Weill Institute for NeurosciencesSan Francisco, California, United StatesRecruiting
University of California, San FranciscoSan Francisco, California, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07288437