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Study identifier: NCT07288398 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

Condition: Pulmonary Hypertension Associated With HFpEF  ·  Sponsor: Tenax Therapeutics, Inc.

PhasePhase 3
Planned participants540
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the efficacy and safety of the study drug, levosimendan (given orally), compared to placebo in participants with pulmonary hypertension with heart failure with preserved left ventricular ejection fraction (PH-HFpEF) as measured by the change in 6-Minute Walk Distance.

This description comes directly from the study's public registry record.

Talk to the study team

Akshata Ashokkumar  ·  (919) 855-2118  ·  a.ashokkumar@tenaxthera.com

Katelyn Jansson  ·  (919) 855-2119  ·  k.jansson@tenaxthera.com

Always discuss trial participation with your own doctor first.

Locations (92)

Tenax Investigational SiteAlexander City, Alabama, United StatesRecruiting
Tenax Investigational SiteTamarac, Florida, United StatesNot Yet Recruiting
Tenax Investigational SiteMount Prospect, Illinois, United StatesNot Yet Recruiting
Tenax Investigational SitePeoria, Illinois, United StatesRecruiting
Tenax Investigational SiteNew Orleans, Louisiana, United StatesRecruiting
Tenax Investigational SiteWest Monroe, Louisiana, United StatesRecruiting
Tenax Investigational SiteYpsilanti, Michigan, United StatesNot Yet Recruiting
Tenax Investigational SiteReno, Nevada, United StatesRecruiting
Tenax Investigational SiteNew York, New York, United StatesNot Yet Recruiting
Tenax Investigational SiteWinston-Salem, North Carolina, United StatesRecruiting
Tenax Investigational SiteAllentown, Pennsylvania, United StatesNot Yet Recruiting
Tenax Investigational SiteWynnewood, Pennsylvania, United StatesNot Yet Recruiting

+ 80 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07288398