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Study identifier: NCT07288138 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

Condition: Metabolic Dysfunction-associated Steatohepatitis  ·  Sponsor: Eccogene

PhasePhase 2
Planned participants160
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The primary objective of this trial is to evaluate the dose-dependent and comparative effects of ECC4703 (low and high dose), ECC0509 (low and high dose), and their combination on hepatic fat reduction as assessed by change in magnetic resonance imaging proton density fat fraction (MRI-PDFF) at Week 12.

This description comes directly from the study's public registry record.

Talk to the study team

Eccogene Clinical Trials  ·  86-21-61053022  ·  contact@eccogene.com

Always discuss trial participation with your own doctor first.

Locations (62)

Arizona Liver HealthChandler, Arizona, United StatesRecruiting
Arizona Liver Health - PeoriaPeoria, Arizona, United StatesRecruiting
Adobe Clinical Research, LLCTucson, Arizona, United StatesRecruiting
Arizona Liver Health - TucsonTucson, Arizona, United StatesRecruiting
Arkansas Gastroenterology, P.ALittle Rock, Arkansas, United StatesRecruiting
ARcare Center for Clinical ResearchLittle Rock, Arkansas, United StatesRecruiting
Om ResearchApple Valley, California, United StatesRecruiting
ARK Clinical Research - Fountain ValleyFountain Valley, California, United StatesRecruiting
Om ResearchLancaster, California, United StatesRecruiting
Ark Clinical ResearchLong Beach, California, United StatesRecruiting
Knowledge Research CenterOrange, California, United StatesRecruiting
Om ResearchVictorville, California, United StatesRecruiting

+ 50 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07288138