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Study identifier: NCT07288021 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)

Condition: Labor, Induced  ·  Sponsor: Bnai Zion Medical Center

PhasePhase 4
Planned participants200
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by pregnant individuals. All participants are 18 or older, carrying a singleton in vertex position and in need of labor induction, are late-preterm or term (34 weeks gestation and onward) and without contraindication to vaginal delivery. Investigators seek to compare pain levels and patient satisfaction between two groups: Nulliparous patients, using EMLA or placebo (randomized, double blinded). Multiparous patients, EMLA or placebo.

This description comes directly from the study's public registry record.

Talk to the study team

Dafna Ben Yehuda Raz, MD, resident doctor  ·  +97248359366  ·  dafna.ben-yehuda@b-zion.org.il

Inna Bleicher, MD, MFM specialist  ·  +97248359366  ·  inna.bleicher@b-zion.org.il

Always discuss trial participation with your own doctor first.

Locations (1)

Bnai Zion Medical CenterHaifa, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT07288021