Condition: Breast Neoplasms · Sponsor: Eli Lilly and Company
This study will include two groups of patients: Cohort 1 and Cohort 2. Cohort 1: will help researchers learn how a medicine called imlunestrant (LY3484356) affects a specific type of breast cancer. Some patients will take both imlunestrant and another treatment to suppress their ovarian function. Some will take it without ovarian suppression. Researchers will compare the effects in breast cancer cells to those of another medicine called tamoxifen. All patients in this group will be premenopausal women who have a type of early breast cancer called estrogen receptor-positive, HER2-negative. The treatment in this group will last for up to 29 days. Cohort 2: will help researchers understand how imlunestrant affects the ovaries when it is taken without ovarian suppression. Researchers will compare the effects to those of another medicine called tamoxifen. This group will also include premenopausal women with the same type of breast cancer. The treatment in this group will last for up to 6 months.
This description comes directly from the study's public registry record.
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or · 1-317-615-4559 · LillyTrials@Lilly.com
Physicians interested in becoming principal investigators please contact · clinical_inquiry_hub@lilly.com
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham | Birmingham, Alabama, United States | Not Yet Recruiting |
| Ironwood Cancer & Research Centers | Chandler, Arizona, United States | Suspended |
| USC/Norris Comprehensive Cancer Center | Los Angeles, California, United States | Not Yet Recruiting |
| UCLA Hematology/Oncology - Parkside | Santa Monica, California, United States | Not Yet Recruiting |
| Banner MD Anderson Cancer Center at North Colorado Medical Center | Greeley, Colorado, United States | Not Yet Recruiting |
| Banner MD Anderson Cancer Center at McKee Medical Center | Loveland, Colorado, United States | Not Yet Recruiting |
| AdventHealth Altamonte Springs | Altamonte Springs, Florida, United States | Not Yet Recruiting |
| Winship Cancer Institute | Atlanta, Georgia, United States | Not Yet Recruiting |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis, Indiana, United States | Recruiting |
| University of Kentucky Chandler Medical Center | Lexington, Kentucky, United States | Not Yet Recruiting |
| Massachusetts General Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| Dana-Farber Cancer Institute | Boston, Massachusetts, United States | Not Yet Recruiting |
+ 66 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07287098