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Study identifier: NCT07286175 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

Condition: Bipolar Disorder  ·  Sponsor: Eli Lilly and Company

PhasePhase 2
Planned participants400
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC), compared with placebo plus SoC in delaying the worsening of bipolar disorder symptoms. The trial is divided into three periods as follows: Screening period that will last approximately 1 month, treatment period that will last a minimum of 6 months, and the follow up period that will last approximately 2 months. The duration of study participation may vary and may be shortened if bipolar symptoms worsen or if withdrawal from the study occurs for any reason.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (87)

ATP Clinical ResearchOrange, California, United StatesRecruiting
Yale University School of MedicineNew Haven, Connecticut, United StatesRecruiting
AGA Clinical TrialsHialeah, Florida, United StatesRecruiting
Accel Research Sites - Maitland Clinical Research UnitMaitland, Florida, United StatesRecruiting
K2 Medical Research - MaitlandMaitland, Florida, United StatesRecruiting
Floridian Clinical Research, LLCMiami Lakes, Florida, United StatesRecruiting
CLA ResearchNaples, Florida, United StatesRecruiting
Charter Research - OrlandoOrlando, Florida, United StatesRecruiting
Encore Medical Research - WestonWeston, Florida, United StatesRecruiting
Atlanta Center for Medical ResearchAtlanta, Georgia, United StatesRecruiting
Covenant Medical CenterWaterloo, Iowa, United StatesRecruiting
CBH HealthGaithersburg, Maryland, United StatesRecruiting

+ 75 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07286175