← Eichor
Study identifier: NCT07286149 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

Condition: Lung Neoplasm Malignant  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 1/Phase 2
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers want to learn if MK-1084, the study medicine, can treat advanced or metastatic non-squamous NSCLC. MK-1084 is a targeted therapy, which is a treatment that works to control how specific types of cancer cells grow and spread. The goals of this study are to learn: * About the safety of MK-1084 and if people tolerate it when taken with other treatments * How many people have the cancer respond (get smaller or go away) to the treatments

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (25)

Clermont Oncology Center ( Site 0041)Clermont, Florida, United StatesRecruiting
University of Illinois Hospital & Health Sciences System ( Site 0044)Chicago, Illinois, United StatesRecruiting
Providence Portland Medical Center ( Site 0043)Portland, Oregon, United StatesRecruiting
Providence Oncology and Hematology Care Clinic - Westside ( Site 0059)Portland, Oregon, United StatesRecruiting
Hospital São Lucas da PUCRS ( Site 0283)Porto Alegre, Rio Grande do Sul, BrazilRecruiting
Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0282)Barretos, São Paulo, BrazilRecruiting
Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 0286)São José do Rio Preto, São Paulo, BrazilRecruiting
Hospital Paulistano ( Site 0280)São Paulo, São Paulo, BrazilRecruiting
Centro de Estudios Clínicos SAGA-CECSAGA ( Site 0162)Santiago, Region M. de Santiago, ChileRecruiting
FALP ( Site 0161)Santiago, Region M. de Santiago, ChileRecruiting
Bradfordhill ( Site 0160)Santiago, Region M. de Santiago, ChileRecruiting
Guangdong Provincial People s Hospital ( Site 0300)Guangzhou, Guangdong, ChinaRecruiting

+ 13 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07286149