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Study identifier: NCT07286123 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gender Affirming Vaginoplasty With Tubularized Augmented Peritoneal Cap (TAPCap) Utilizing Fish Skin Xenograft (Kerecis™)

Condition: Gender Dysphoria, Adult  ·  Sponsor: University Hospitals Cleveland Medical Center

PhaseN/A
Planned participants20
Who can joinMale, 19 Years to 99 Years
Healthy volunteersNo

About this study

Bottom gender affirming surgery is one of the key steps towards aligning the physical appearance and gender identity in transgender women. This surgery not only helps in reducing gender dysphoria but also significantly improves the quality of life and psychological well-being of the patients. The basic steps of bottom surgery typically involve the creation of a vagina using the skin from genital organs like the testes and penis, construction of the clitoris and labia. This complex surgery aims to create a functional and aesthetically pleasing vaginal canal that allows for sexual activity, urinary function, and a natural appearance. As part of routine care, a special graft (skin-like material) called Kerecis™ is used to line the middle part of the vagina. It is made from North Atlantic cod skin that is treated in the laboratory and made suitable for surgery purposes. It can be used instead of skin. This graft has been given permission by the Food and Drug Administration (FDA) for marketing the US. This study aims to identify changes in healing parameters following Kerecis™ based vaginoplasty. Up to 20 participants for this study. Participants will be asked to fill out study questionnaires during follow-up visits at post-op week 2, week 12, month , and year 1. At the 6 month post-op follow up, punch biopsies will be obtained from the deepest part, middle part, and the vaginal part most near to the vaginal opening parts to check the healing process using a microscope. The pu…

This description comes directly from the study's public registry record.

Talk to the study team

Seyed Sajjad Tabei, MD  ·  216-844-8963  ·  seyedsajjad.tabei@uhhospitals.org

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospitals Cleveland Medical CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07286123