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Study identifier: NCT07285850 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Efficacy of Sequential Treatment With Bevacizumab Combined With Atezolizumab in Advanced Liver Cancer With MASLD

Condition: HCC - Hepatocellular Carcinoma  ·  Sponsor: Eastern Hepatobiliary Surgery Hospital

PhasePhase 2/Phase 3
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This research plan involves a treatment approach for advanced hepatocellular carcinoma (HCC) in the context of metabolic-associated steatotic liver disease (MASLD). The study aims to compare the efficacy differences between sequential therapy and concurrent therapy using bevacizumab and atezolizumab for advanced HCC in MASLD. The research will focus on evaluating objective response rates, progression-free survival, disease control rates, and overall survival, while utilizing biomarker analysis to elucidate treatment mechanisms. Additionally, the study will examine treatment safety, including the incidence and severity of adverse events.

This description comes directly from the study's public registry record.

Talk to the study team

Hao Shen, M.D.  ·  18952681068  ·  shenhaochina@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Eastern Hepatobiliary Surgery HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07285850