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Study identifier: NCT07284797 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases

Condition: Healthy · Idiopathic Inflammatory Myopathies · Systemic Sclerosis  ·  Sponsor: Xencor, Inc.

PhasePhase 1
Planned participants60
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

The purpose of this study is to determine the safety and tolerability of XmAb657 in healthy participants and participants with autoimmune diseases. Participants will be given XmAb657 subcutaneously (SC) by injection under the skin.

This description comes directly from the study's public registry record.

Talk to the study team

Noriko Iikuni, MD, PhD  ·  657-aiinfo@xencor.com

Jaime Mertz  ·  657-aiinfo@xencor.com

Always discuss trial participation with your own doctor first.

Locations (1)

Xencor Investigative SiteMelbourne, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT07284797