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Study identifier: NCT07284615 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial

Condition: Arthropathy of Hip · Hip Arthropathy · Locoregional Anesthesia  ·  Sponsor: Ospedale Edoardo Bassini

PhaseNA
Planned participants102
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective, randomized controlled trial aims to compare two multimodal regional anesthesia strategies for postoperative analgesia in elective total hip arthroplasty (THA) performed via anterior approach. Patients will be randomized to receive either a Pericapsular Nerve Group (PENG) block combined with a Lateral Femoral Cutaneous Nerve (LFCN) block, or a PENG block combined with wound infiltration (WI). The primary outcome is postoperative pain intensity at rest, measured by Numerical Rating Scale (NRS) at 6 hours after surgery. Secondary outcomes include dynamic pain scores at 6, 24, and 48 hours, total opioid consumption, time to first rescue analgesia, quadriceps strength, hip flexion angle, length of stay, and adverse events. All procedures are routinely used in clinical practice and carry minimal additional risk. Safety will be continuously monitored by the Principal Investigator and the study team according to an internal Safety Monitoring Plan.

This description comes directly from the study's public registry record.

Talk to the study team

Matteo Coccolo, MD  ·  0039025799  ·  matteo.coccolo@asst-nordmilano.it

Angelo Pezzi, MD  ·  0039025799  ·  angelo.pezzi@asst-nordmilano.it

Always discuss trial participation with your own doctor first.

Locations (1)

Ospedale Edoardo BassiniCinisello Balsamo, Milano, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07284615