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Study identifier: NCT07282912 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

Condition: Foregut Adenocarcinoma · Esophageal Adenocarcinoma · Gastroesophageal Adenocarcinoma  ·  Sponsor: Yale University

PhasePhase 2
Planned participants54
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a randomized, open label, single-center, phase 2, randomized controlled trial of sequential cytoreductive intervention versus standard of care therapy for patients with intervenable oligometastatic (stage IV) cancer of the upper gastrointestinal (GI) tract and undetectable ctDNA at the time of randomization after a three-month induction chemotherapy period.

This description comes directly from the study's public registry record.

Talk to the study team

Wumi Jemiseye, MPH  ·  203-737-4475  ·  wumi.jemiseye@yale.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Smilow Cancer CenterNew Haven, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07282912