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Study identifier: NCT07282834 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)

Condition: Peritoneal (Metastatic) Cancer · Peritoneal Carcinomatosis · Abdominal Cancer  ·  Sponsor: Patrick Wagner, MD, FACS

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This research study aims to improve the treatment of Peritoneal Carcinomatosis (PC), a condition where cancer spreads within the abdomen. Patients with PC often experience significant pain and nutritional problems. Currently, there isn't a standard treatment approach, and doctors use different combinations of chemotherapy, surgery, and methods to deliver chemotherapy directly into the abdomen (intra-peritoneal or "IP" chemotherapy). The study will compare two IP chemotherapy methods: HIPEC and PIPAC. HIPEC involves circulating heated chemotherapy through the abdomen during surgery, while PIPAC delivers chemotherapy as a pressurized aerosol during a laparoscopic procedure. Both methods aim to achieve the same goal, but they haven't been directly compared to see which is safer, more tolerable, more effective, and provides better value.

This description comes directly from the study's public registry record.

Talk to the study team

Patrick Wagner, MD  ·  412-359-3731  ·  patrick.wagner@ahn.org

AHN Clinical Trial Contact Clinical Trial Contact  ·  412-359-3731  ·  clinicaltrials@ahn.org

Always discuss trial participation with your own doctor first.

Locations (1)

Allegheny Health Network West Penn HospitalPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07282834