● Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)

Condition: Progressive Multiple Sclerosis · Sponsor: Hoffmann-La Roche

PhasePhase 2

Planned participants360

Who can joinAll sexes, 18 Years to 60 Years

Healthy volunteersNo

About this study

The main purpose of this study is to assess the efficacy of RO7268489 in adults with progressive multiple sclerosis (PMS) receiving ocrelizumab. After the end of the double-blind period, an open-label (OL) extension may allow eligible participants to receive open-label RO7268489.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: BP46016 https://forpatients.roche.com/ · 888-662-6728 (U.S. Only) · global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. No email attachments. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (103)

Southern Neurology	Kogarah, New South Wales, Australia	Recruiting
John Hunter Hospital	New Lambton Heights, New South Wales, Australia	Recruiting
Box Hill Hospital	Box Hill, Victoria, Australia	Recruiting
Austin Health	Heidelberg, Victoria, Australia	Recruiting
CHU Strasbourg Hpital Hautepierre	Strasbourg, Bas Rhin, France	Recruiting
Hopital Caremeau	Nîmes, Gard, France	Recruiting
Groupe Hospitalier Pellegrin	Bordeaux, Gironde, France	Recruiting
Hopital Purpan	Toulouse, Haute Garonne, France	Recruiting
Hopital Gui de Chauliac	Montpellier, Herault, France	Recruiting
CHU Nantes - Hopital Nord Laënnec	Saint-Herblain, Loire Atlantique, France	Recruiting
CHU Nancy Hôpital Central	Nancy, Meurthe Et Moselle, France	Recruiting
CHU Hopital Gabriel Montpied	Clermont-Ferrand, Puy De Dome, France	Recruiting

+ 91 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07282574