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Study identifier: NCT07282262 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Exploratory Study on the Use of Ivosidenib for the Precise Treatment of Advanced Biliary Tract Malignancies With IDH1 Mutations in the Later Line of Therapy.

Condition: Biliary Tract Cancer  ·  Sponsor: Peking Union Medical College Hospital

PhasePhase 2
Planned participants300
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a multicenter, non-randomized, umbrella, open-label phase II clinical study, aiming to observe and evaluate, as well as explore the efficacy and safety of precision targeted therapy based on NGS technology for IDH1-mutated patients, specifically the combination of ivosidenib with multi-target tyrosine kinase inhibitors represented by lenvatinib or PD-1/PD-L1 in advanced biliary tract cancer patients who have failed systemic chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Chengjie Li  ·  13733879582  ·  1624271942@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Peking Union Medical College Hospital Outpatient DepartmentBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07282262