← Eichor
Study identifier: NCT07278323 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Frozen Shoulder and Hormone Replacement Therapy

Condition: Adhesive Capsulitis of the Shoulder · Frozen Shoulder  ·  Sponsor: University of California, San Francisco

PhasePhase 4
Planned participants60
Who can joinFemale, 40 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, stiffness, and progressive loss of range of motion. Age-related menstrual cycle changes, known as perimenopause and/or menopause, refers to a change or stoppage of monthly menstrual cycles. Other symptoms participants may be experiencing include vaginal dryness, hot flashes, or night sweats. Hormone replacement therapy (HRT) refers to medicine with female hormones in it. For this study, HRT will be in the form of a patch that goes on the skin and a daily oral pill. Participants will be randomly assigned to receive either HRT plus standard care, or only standard care. Follow-up tests will be completed at 6 months of treatment to assess participant progress.

This description comes directly from the study's public registry record.

Talk to the study team

Alexa J Chandler, PhD  ·  (415) 353-2808  ·  alexa.chandler@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCSF Orthopaedic InstituteSan Francisco, California, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07278323