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Study identifier: NCT07277413 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

Condition: NSCLC Adenocarcinoma · Gastroesophageal Cancer (GC) · Gastric Adenocarcinoma  ·  Sponsor: IDEAYA Biosciences

PhasePhase 1
Planned participants260
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in participants with methylthioadenosine phosphorylase (MTAP)-deleted advanced solid tumors within indications of interest.

This description comes directly from the study's public registry record.

Talk to the study team

IDEAYA Clinical Trials  ·  +1 855 433 2246  ·  IDEAYAClinicalTrials@ideayabio.com

Always discuss trial participation with your own doctor first.

Locations (16)

Providence Medical FoundationSanta Rosa, California, United StatesRecruiting
Johns Hopkins Sibley Memorial HospitalWashington D.C., District of Columbia, United StatesRecruiting
BRCR Global-Coral SpringsCoral Springs, Florida, United StatesRecruiting
Sarah Cannon Research Institute at Florida Cancer SpecialistsOrlando, Florida, United StatesRecruiting
Nebraska Cancer SpecialistsOmaha, Nebraska, United StatesRecruiting
START Astera, LLCEast Brunswick, New Jersey, United StatesRecruiting
Columbia University Irving Medical CenterNew York, New York, United StatesRecruiting
Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson UniversityPhiladelphia, Pennsylvania, United StatesRecruiting
Sarah Cannon Research InstituteNashville, Tennessee, United StatesRecruiting
START Dallas Fort WorthFort Worth, Texas, United StatesRecruiting
MD AndersonHouston, Texas, United StatesRecruiting
NEXT Oncology HoustonHouston, Texas, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07277413