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Study identifier: NCT07277309 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Promoting Recovery After Brain Injury Using Focused Ultrasound

Condition: Consciousness Disorders · Disorders of Consciousness Due to Severe Brain Injury  ·  Sponsor: Massachusetts General Hospital

PhaseNA
Planned participants36
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this project aims to (1) determine neurobehavioral responses to low-intensity focused ultrasound (LIFUP) in patients with disorders of consciousness (DoC) following brain injury, (2) determine neurophysiologic (EEG) responses to LIFUP in patients with DoC and (3) identify and evaluate ethical perspectives of patient representatives (family members and surrogate decision-makers) surrounding investigation of therapeutic neuromodulation technologies such as LIFUP in patients with DoC.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Young, MD, MPhil  ·  410-808-1196  ·  michael.young@mgh.harvard.edu

Jason Lew, DO  ·  617-724-9247  ·  jlew3@mgb.org

Always discuss trial participation with your own doctor first.

Locations (2)

Massachusetts General Hospital (The General Hospital Corp.)Boston, Massachusetts, United StatesRecruiting
Spaulding Rehabilitation Hospital Corporation, Inc.Cambridge, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07277309