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Study identifier: NCT07277231 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Condition: Chronic Lymphocytic Leukemia  ·  Sponsor: BeOne Medicines

PhasePhase 3
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to investigate the efficacy and safety of fixed-duration sonrotoclax (also known as BGB-11417) plus zanubrutinib (also known as BGB-3111) (SZ) compared with fixed-duration of venetoclax plus acalabrutinib (AV) in participants with previously untreated chronic lymphocytic leukemia (CLL).

This description comes directly from the study's public registry record.

Talk to the study team

Study Director  ·  8778285568  ·  clinicaltrials@beonemed.com

Always discuss trial participation with your own doctor first.

Locations (91)

Stanford Cancer InstitutePalo Alto, California, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Fred Hutchinson Cancer Research CenterSeattle, Washington, United StatesRecruiting
Blacktown Cancer and Haematology CentreBlacktown, New South Wales, AustraliaRecruiting
Concord Repatriation General HospitalConcord, New South Wales, AustraliaRecruiting
Genesiscare North ShoreSt Leonards, New South Wales, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, Queensland, AustraliaRecruiting
Monash HealthClayton, Victoria, AustraliaRecruiting
Austin HealthHeidelberg, Victoria, AustraliaRecruiting
Cabrini Hospital MalvernMalvern, Victoria, AustraliaRecruiting
The Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Instituto Dor de Pesquisa E Ensino Distrito FederalBrasília, BrazilRecruiting

+ 79 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07277231