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Study identifier: NCT07276035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Brain-Stomach Circuits in Chronic Nausea

Condition: Chronic Nausea and Vomiting Syndrome  ·  Sponsor: David Levinthal

PhaseNA
Planned participants219
Who can joinAll sexes, 21 Years to 60 Years
Healthy volunteersYes

About this study

The goal of this study is to determine whether stimulation of the brain-stomach connection can influence stomach activity in healthy adults and in individuals suffering from chronic nausea. The main questions it aims to answer are: * What are the best brain sites to influence the stomach? * What are the effects of different stimulation patterns on stomach activity? * Does the stimulation affect the sensation of nausea in participants suffering from chronic nausea? Researchers will use a non-invasive method of brain stimulation called Transcranial Magnetic Stimulation (TMS) and will record stomach responses with skin electrodes on the abdomen. Participants will: * Visit the clinic at least once, and for up to 9 times more over the course of several months. * Receive TMS while sitting in a chair similar to a dentist's chair. * Drink water or consume a test meal during each study visit.

This description comes directly from the study's public registry record.

Talk to the study team

Elijah D Wright  ·  412-647-1228  ·  edw87@pitt.edu

David J Levinthal, MD PhD  ·  412-303-0525  ·  levinthald@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07276035